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Direct head-to-head data against tirzepatide showed CagriSema underperforming the highest tirzepatide dose at 84 weeks meaning monotherapy claims of comparable efficacy are not supported by current Phase 3 evidence

It's a good option for those looking to avoid high doses, but the daily serving of six large capsules may be a drawback for some, and the inclusion of vitamin K means it may not be appropriate if you're on blood thinners

Individual variation in response timing is normal and expected

IL-6 and IL-17A can cross the placenta or stimulate placental cytokine cascades that indirectly affect the fetal brain

[1] [2] The pharmacological effects of tirzepatide create unique nutritional considerations

It is important to follow recommended doses to ensure both effectiveness and safety